In vivo Molecular Imaging at Cellular Resolution
Visit us at WMIC on Booth #323
Features
The Cellvizio Dual Band incorporates color into the state of the art in vivo molecular imaging system. This allows researchers to visualize both invaluable anatomical and functional information. The company is unveiling the new product at the World Molecular Imaging Congress, taking place in Dublin, September 5th to 8th.
"With the Cellvizio Dual Band, we can now offer laboratories additional information about live, in vivo cellular interaction that will provide researchers with the ability to observe anatomical and functional activity as it happens. The ability to see and monitor internal physiological processes at the cellular level helps researchers gain new understanding of the root causes of disease and disorders," said Sacha Loiseau, Ph.D., CEO and Founder of Mauna Kea Technologies. "This represents an important milestone for the company and demonstrates our ongoing commitment to remain at the forefront of innovation in the imaging market."
In vivo small animal imaging is used in pre-clinical research at academic institutions and biotechnological and pharmaceutical companies. Such experiments play a key role in neurological research of the deep brain and peripheral nerves, especially in the research of degenerative diseases such as Alzheimer's and Parkinson's. Other applications of Cellvizio Dual Band include cancer, cardiovascular, stem cell research, gene delivery and tissue engineering research.
The Cellvizio Dual Band offers researchers enhanced analysis opportunities through the utilization of contrasti agents while maintaining the same ground-breaking microscopic resolution as the family of Cellvizio probes used clinically today.
The system features:
- Real time, Simultaneous imaging at 488 nm and 660 nm
- A broad range of flexible microprobes for diverse and combined applications
- Quantitative, single photon counting
- Acquire, Process, Quantify and Export
- A new, intuitive user interface
Applications
Your Imagination is the Limit
Cellvizio Lab provides mini-invasive access any organ or tissue thanks to its ground-breaking micro-invasive microprobes. The applications range from cancer research to neuroscience, and include diverse subjects such as immunology, inflammation, functional imaging, or biomarker distribution.
Cellvizio Dual Band in vivo monitors colocalization and highlights cellular interactions as well as structure-function correlations.
Thanks to its widely used wavelengths, Cellvizio is compatible with many fluorescent dyes and proteins. Molecular markers like AvB3 Integrin dyes, Sytox Green, GCaMP3, (Neuronal function imaging) are just a few examples.
- Structure - function imaging
- Colocalization and interactions
- Functional imaging
- Biodistribution
- Animal model validation
- Longitudinal studies
- Angiogenesis
- Deep brain imaging on awake animals
- Molecular imaging of cancer mechanisms
- in vivo histology and histopathology
Application Outcomes
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Renal elimination of AvB3 Integrin marker Microprobe S1500 |
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Tumor vasculature network stained with FITC Dextran that interact with macrophages Microprobe UltraM |
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Spleen imaging after injection of AminoSpark (Red) and FITC Dextran (Green) Microprobe UltraM |
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Inflammation process ongoing around tumoral vessels and the tumor associated macrophages surrounding them Microproble UltraM |
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AngioStamp®, a nIR endothelial cells molecular marker is closely distributed around the vessels Z1800 Microprobe |
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Colon crypts imaged after acryflavin and AngioSense 680 injection: Vessels are highlighted in red, and crypts in green S1500 Microprobe |
Technical Specifications
Cellvizio® Dual Band |
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Excitation Wavelengths |
Laser 1: 488 nm |
Laser 2: 660 nm |
Collection Bandwidths |
505 - 700 nm |
680 - 900 nm |
Temporal Resolution |
9 frames per second |
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Signal Encoding |
14 bits |
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Image Export |
.png, .bmp, . jpeg, .tiff, .mhd |
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Movie Export |
.avi, .mpeg, .mp4, .swf, |
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Power Requirements |
150 W (110 - 240 V) |
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Laser Class |
2M |
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Size and Weight |
480 x 260 x 500 mm, 28 kg |
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Included Software |
Cellvizio Dual Software - Cellvizio Dual Viewer |
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Events
We are in a scientific environment in which ideas are nurtured, collaboration is encouraged and innovation flourishes. Our passion for innovation has produced a new system backed by one of the most talented teams in the industry.
The result: A fully multiplexed Cellvizio Dual Band that will be officially showcased at the WMIC Dublin 2012.
The Convention Centre Dublin (CCD)
Dublin, Ireland
World Molecular Imaging Congress
September 5-8, 2012
Discover
on our Booth #323
Contact
For more information, please drop an email at cellviziolab@maunakeatech.com
For more information on Cellvizio go to: www.maunakeatech.com
Mauna Kea Technologies |
Mauna Kea Technologies Inc. 3240 South White Road., Suite 112 San Jose, CA 95148 USA Tel: + 1 408-729-3155 Fax: + 1 408-729-1889 Toll free: + 1 888 590 1798 |
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